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Quantifying Single mRNA Translation Kinetics in Living Cells

One of the last hurdles to quantifying the full central dogma of molecular biology in living cells with single-molecule resolution has been the imaging of single messenger RNA (mRNA) translation. Here we describe how recent advances in protein tagging and imaging technologies are being used to preci...

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Détails bibliographiques
Publié dans:Cold Spring Harb Perspect Biol
Auteurs principaux: Morisaki, Tatsuya, Stasevich, Timothy J.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6211384/
https://ncbi.nlm.nih.gov/pubmed/30385605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a032078
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