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Telomere maintenance: regulating hTERC fate through RNA modifications
Disturbances in telomere maintenance are common in cancer. We recently showed that Single-strand-selective monofunctional uracil-DNA glycosylase 1 (SMUG1) promotes telomere homeostasis by regulating the stability of the telomeric RNA component (hTERC). SMUG1-mediated recognition of base modification...
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| Published in: | Mol Cell Oncol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6816388/ https://ncbi.nlm.nih.gov/pubmed/31692866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1670489 |
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