Process intensification in fed-batch production bioreactors using non-perfusion seed cultures

Although process intensification by continuous operation has been successfully applied in the chemical industry, the biopharmaceutical industry primarily uses fed-batch, rather than continuous or perfusion methods, to produce stable monoclonal antibodies (mAbs) from Chinese hamster ovary (CHO) cells...

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Bibliografiske detaljer
Udgivet i:MAbs
Main Authors: Yongky, Andrew, Xu, Jianlin, Tian, Jun, Oliveira, Christopher, Zhao, Jia, McFarland, Kevin, Borys, Michael C., Li, Zheng Jian
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816350/
https://ncbi.nlm.nih.gov/pubmed/31379298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1652075
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