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Reduced expression of PD-L1 in autoimmune thyroiditis attenuate trophoblast invasion through ERK/MMP pathway

BACKGROUND: Autoimmune thyroiditis (AIT) with euthyroid is associated with miscarriage. But the exact mechanism remains unclear. Studies have shown that the programmed cell death-1 (PD-1)/programmed cell death -ligand 1 (PD-L1) pathway is essential for normal pregnancy. However, the expression of PD...

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Detalhes bibliográficos
Publicado no:Reprod Biol Endocrinol
Main Authors: Chen, Mengya, Gilbert, Nduwimana, Liu, Haixia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816196/
https://ncbi.nlm.nih.gov/pubmed/31656199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-019-0536-1
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