Trop2 enhances invasion of thyroid cancer by inducing MMP2 through ERK and JNK pathways

BACKGROUND: Mounting evidence has showed that Tumor-associated calcium signal transducer 2 (Trop2) is upregulated in various kinds of human cancers and plays important roles in tumorigenesis. However, the expression status and functional significance of Trop2 in thyroid cancer are largely unknown. M...

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Vydáno v:BMC Cancer
Hlavní autoři: Guan, Hongyu, Guo, Zejun, Liang, Weiwei, Li, Hai, Wei, Guohong, Xu, Lijuan, Xiao, Haipeng, Li, Yanbing
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513028/
https://ncbi.nlm.nih.gov/pubmed/28709407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3475-2
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