Effects of VEGF blockade on the dynamics of the inflammatory landscape in glioblastoma-bearing mice

BACKGROUND: Targeting angiogenesis has been and continues to be an attractive therapeutic modality in glioblastoma (GBM) patients. However, GBM rapidly becomes refractory to anti-VEGF therapies. Myeloid cell infiltration is an important determinant of tumor progression. Given that VEGF is a modulato...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Soubéran, Aurélie, Brustlein, Sophie, Gouarné, Caroline, Chasson, Lionel, Tchoghandjian, Aurélie, Malissen, Marie, Rougon, Geneviève
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816183/
https://ncbi.nlm.nih.gov/pubmed/31660979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1563-8
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