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Cross-species comparison of CAR-mediated procarcinogenic key events in a 3D liver microtissue model
Characterisation of the mode of action (MOA) of constitutive androstane receptor (CAR)-mediated rodent liver tumours involves measurement 5 key events including activation of the CAR receptor, altered gene expression, hepatocellular proliferation, clonal expansion and increased hepatocellular adenom...
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| Publicado no: | Toxicol Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6816142/ https://ncbi.nlm.nih.gov/pubmed/31673501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2019.09.010 |
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