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Species differences in phenobarbital-mediated UGT gene induction in rat and human liver microtissues
Species differences in hepatic metabolism of thyroxine (T4) by uridine diphosphate glucuronosyl transferase (UGT) and susceptibility to thyroid hormone imbalance could underlie differences in thyroid carcinogenesis caused by hepatic enzyme inducers in rats and humans. To investigate this hypothesis...
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| Publicado no: | Toxicol Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7803626/ https://ncbi.nlm.nih.gov/pubmed/33473352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2020.12.019 |
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