Rapid Transduction and Expansion of Transduced T Cells with Maintenance of Central Memory Populations

Chimeric antigen receptor (CAR)-T cells show great promise in treating cancers and viral infections. However, most protocols developed to expand T cells require relatively long periods of time in culture, potentially leading to progression toward populations of terminally differentiated effector mem...

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Pubblicato in:Mol Ther Methods Clin Dev
Autori principali: Pampusch, Mary S., Haran, Kumudhini Preethi, Hart, Geoffrey T., Rakasz, Eva G., Rendahl, Aaron K., Berger, Edward A., Connick, Elizabeth, Skinner, Pamela J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816036/
https://ncbi.nlm.nih.gov/pubmed/31673565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.09.007
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