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Exosomes from nicotine-stimulated macrophages accelerate atherosclerosis through miR-21-3p/PTEN-mediated VSMC migration and proliferation

Rationale: During the development of atherosclerosis, macrophages secrete exosomes that regulate vascular smooth muscle cells (VSMCs); however, whether nicotine, a major constituent of cigarettes, can modulate this communication in the context of atherogenesis remains to be further studied. In this...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Zhu, Jumo, Liu, Bei, Wang, Zhiyan, Wang, Di, Ni, Huaner, Zhang, Lili, Wang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815950/
https://ncbi.nlm.nih.gov/pubmed/31660076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.37357
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