The N‐terminal D1 domain of Treponema pallidum flagellin binding to TLR5 is required but not sufficient in activation of TLR5

Syphilis is a chronic bacterial infection caused by Treponema pallidum (T pallidum) and the pathogenesis that T pallidum infection induces immunopathological damages in skin and other tissues remains unclear. We have previously reported that recombinant flagellins of T pallidum can elicit IL‐6 and I...

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Bibliographic Details
Published in:J Cell Mol Med
Main Authors: Xu, Man, Xie, Yafeng, Tan, Manyi, Zheng, Kang, Xiao, Yongjian, Jiang, Chuanhao, Zhao, Feijun, Zeng, Tiebing, Wu, Yimou
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815820/
https://ncbi.nlm.nih.gov/pubmed/31493340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14617
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