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Tumor-specific delivery of gemcitabine with activatable liposomes
Gemcitabine delivery to pancreatic ductal adenocarcinoma is limited by poor pharmacokinetics, dense fibrosis and hypo-vascularization. Activatable liposomes, with drug release resulting from local heating, enhance serum stability and circulation, and the released drug retains the ability to diffuse...
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| Publicado no: | J Control Release |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6815719/ https://ncbi.nlm.nih.gov/pubmed/31301340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.07.014 |
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