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Inhibiting PI3 Kinase-γ in Both Myeloid and Plasma Cells Remodels the Suppressive Tumor Microenvironment in Desmoplastic Tumors
Phosphoinositide-3-kinases (PI3Ks) are part of signal transducing enzymes that mediate key cellular functions in cancer and immunity. PI3K-γ is crucial for cellular activation and migration in response to certain chemokines. PI3K-γ is highly expressed in myeloid cells and promotes their migration an...
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| Veröffentlicht in: | J Control Release |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6815713/ https://ncbi.nlm.nih.gov/pubmed/31362079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.07.039 |
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