Polo-like kinase 3 inhibits glucose metabolism in colorectal cancer by targeting HSP90/STAT3/HK2 signaling

BACKGROUND: Polo-like kinase 3 (PLK3) has been documented as a tumor suppressor in several types of malignancies. However, the role of PLK3 in colorectal cancer (CRC) progression and glucose metabolism remains to be known. METHODS: The expression of PLK3 in CRC tissues was determined by immunohistoc...

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Bibliographic Details
Published in:J Exp Clin Cancer Res
Main Authors: Ou, Baochi, Sun, Hongze, Zhao, Jingkun, Xu, Zhuoqing, Liu, Yuan, Feng, Hao, Peng, Zhihai
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815449/
https://ncbi.nlm.nih.gov/pubmed/31655629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1418-2
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