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Temperature-Jump Solution X-ray Scattering Reveals Distinct Motions in a Dynamic Enzyme

Correlated motions of proteins are critical to function, but these features are difficult to resolve using traditional structure determination techniques. Time-resolved X-ray methods hold promise for addressing this challenge but have relied on the exploitation of exotic protein photoactivity, and a...

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Vydáno v:Nat Chem
Hlavní autoři: Thompson, Michael C., Barad, Benjamin A., Wolff, Alexander M., Cho, Hyun Sun, Schotte, Friedrich, Schwarz, Daniel M.C., Anfinrud, Philip, Fraser, James S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815256/
https://ncbi.nlm.nih.gov/pubmed/31527847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-019-0329-3
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