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The Role of Sugar-backbone Heterogeneity and Chimeras in the Simultaneous Emergence of RNA and DNA

Hypotheses of the origins of RNA and DNA are generally centered on the prebiotic synthesis of a pristine system (pre-RNA or RNA), which gives rise to its descendent. However, a lack of specificity in the synthesis of genetic polymers would likely result in chimeric sequences; the roles and fate of s...

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Veröffentlicht in:Nat Chem
Hauptverfasser: Bhowmik, Subhendu, Krishnamurthy, Ramanarayanan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815252/
https://ncbi.nlm.nih.gov/pubmed/31527850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-019-0322-x
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