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Orotidine-Containing RNA: Implications for the Hierarchical Selection (Systems Chemistry Emergence) of RNA

The prebiotic synthesis of canonical nucleobases from HCN is a cornerstone for the RNA world hypothesis. However, their role in the primordial pathways to RNA is still debated. The very same process starting from HCN also gives rise to orotic acid, which (via orotidine) plays a crucial role in extan...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Kim, Eun-Kyong, Martin, Vincent, Krishnamurthy, Ramanarayanan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311447/
https://ncbi.nlm.nih.gov/pubmed/28708927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201702912
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