Significant association of rare variant p.Gly8Ser in cardiac sodium channel β4-subunit SCN4B with atrial fibrillation

Atrial fibrillation (AF) affects 33.5 million individuals worldwide. It accounts for 15% of strokes and increases risk of heart failure and sudden death. The voltage-gated cardiac sodium channel complex is responsible for the generation and conduction of the cardiac action potential, and composed of...

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Udgivet i:Ann Hum Genet
Main Authors: Xiong, Hongbo, Yang, Qin, Zhang, Xiaoping, Wang, Pengxia, Chen, Feifei, Liu, Ying, Wang, Pengyun, Zhao, Yuanyuan, Li, Sisi, Huang, Yufeng, Chen, Shanshan, Wang, Xiaojing, Zhang, Hongfu, Yu, Dong, Tan, Chencheng, Fang, Cheng, Huang, Yuan, Wu, Gang, Wu, Yanxia, Cheng, Xiang, Liao, Yuhua, Zhang, Rongfeng, Yang, Yanzong, Ke, Tie, Ren, Xiang, Li, Hui, Tu, Xin, Xia, Yunlong, Xu, Chengqi, Chen, Qiuyun, Wang, Qing K.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815221/
https://ncbi.nlm.nih.gov/pubmed/30821358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ahg.12305
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