Screening Legionella effectors for antiviral effects reveals Rab1 GTPase as a proviral factor coopted for tombusvirus replication

Bacterial virulence factors or effectors are proteins targeted into host cells to coopt or interfere with cellular proteins and pathways. Viruses often coopt the same cellular proteins and pathways to support their replication in infected cells. Therefore, we screened the Legionella pneumophila effe...

Full description

Saved in:
Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Inaba, Jun-ichi, Xu, Kai, Kovalev, Nikolay, Ramanathan, Harish, Roy, Craig R., Lindenbach, Brett D., Nagy, Peter D.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815150/
https://ncbi.nlm.nih.gov/pubmed/31591191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911108116
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items