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Pleiotropy informed adaptive association test of multiple traits using GWAS summary data

Genetic variants associated with disease outcomes can be used to develop personalized treatment. To reach this precision medicine goal, hundreds of large-scale genome-wide association studies (GWAS) have been conducted in the past decade to search for promising genetic variants associated with vario...

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書目詳細資料
發表在:Biometrics
Main Authors: Masotti, Maria, Guo, Bin, Wu, Baolin
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814451/
https://ncbi.nlm.nih.gov/pubmed/31021400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.13076
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