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Powerful and efficient SNP-set association tests across multiple phenotypes using GWAS summary data

MOTIVATION: Many GWAS conducted in the past decade have identified tens of thousands of disease related variants, which in total explained only part of the heritability for most traits. There remain many more genetics variants with small effect sizes to be discovered. This has motivated the developm...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Guo, Bin, Wu, Baolin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477978/
https://ncbi.nlm.nih.gov/pubmed/30239606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty811
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