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Powerful and efficient SNP-set association tests across multiple phenotypes using GWAS summary data

MOTIVATION: Many GWAS conducted in the past decade have identified tens of thousands of disease related variants, which in total explained only part of the heritability for most traits. There remain many more genetics variants with small effect sizes to be discovered. This has motivated the developm...

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Vydáno v:Bioinformatics
Hlavní autoři: Guo, Bin, Wu, Baolin
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477978/
https://ncbi.nlm.nih.gov/pubmed/30239606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty811
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