Intestinal Epithelial Cell–Derived LKB1 Suppresses Colitogenic Microbiota

Dysregulation of the immune barrier function of the intestinal epithelium can often result in dysbiosis. In this study we report a novel role of intestinal epithelial cell (IEC)-derived liver kinase B1 (LKB1) in suppressing colitogenic microbiota. IEC-specific deletion of LKB1 (LKB1(ΔIEC)) resulted...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Liu, Xia’nan, Lu, Jinfeng, Liu, Zhenshan, Zhao, Junjie, Sun, Hongxiang, Wu, Ningbo, Liu, Hongzhi, Liu, Weiwei, Hu, Zhuqin, Meng, Guangxun, Shen, Lei, Miller, Aaron W., Su, Bing, Li, Xiaoxia, Kang, Zizhen
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814173/
https://ncbi.nlm.nih.gov/pubmed/29352002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700547
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