Exome Sequencing in BRCA1- and BRCA2-Negative Greek Families Identifies MDM1 and NBEAL1 as Candidate Risk Genes for Hereditary Breast Cancer

Approximately 10% of breast cancer (BC) cases are hereditary BC (HBC), with HBC most commonly encountered in the context of hereditary breast and ovarian cancer (HBOC) syndrome. Although thousands of loss-of-function (LoF) alleles in over 20 genes have been associated with HBC susceptibility, the ge...

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Bibliografische gegevens
Gepubliceerd in:Front Genet
Hoofdauteurs: Glentis, Stavros, Dimopoulos, Alexandros C., Rouskas, Konstantinos, Ntritsos, George, Evangelou, Evangelos, Narod, Steven A., Mes-Masson, Anne-Marie, Foulkes, William D., Rivera, Barbara, Tonin, Patricia N., Ragoussis, Jiannis, Dimas, Antigone S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019
Onderwerpen:
Genetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813924/
https://ncbi.nlm.nih.gov/pubmed/31681433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.01005
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