Bioengineered scaffolds for 3D culture demonstrate extracellular matrix-mediated mechanisms of chemotherapy resistance in glioblastoma

Originating in the brain, glioblastoma (GBM) is a highly lethal and virtually incurable cancer, in large part because it readily develops resistance to treatments. While numerous studies have investigated mechanisms enabling GBM cells to evade chemotherapy-induced apoptosis, few have addressed how t...

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Bibliografiset tiedot
Julkaisussa:Matrix Biol
Päätekijät: Xiao, Weikun, Wang, Shanshan, Zhang, Rongyu, Sohrabi, Alireza, Yu, Qi, Liu, Sihan, Ehsanipour, Arshia, Liang, Jesse, Bierman, Rebecca D., Nathanson, David A., Seidlits, Stephanie K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813884/
https://ncbi.nlm.nih.gov/pubmed/31028838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2019.04.003
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