iPSC-derived homogeneous populations of developing schizophrenia cortical interneurons have compromised mitochondrial function

Schizophrenia (SCZ) is a neurodevelopmental disorder. Thus, studying pathogenetic mechanisms underlying SCZ requires studying the development of brain cells. Cortical interneurons (cINs) are consistently observed to be abnormal in SCZ postmortem brains. These abnormalities may explain altered gamma...

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Udgivet i:Mol Psychiatry
Main Authors: Ni, Peiyan, Noh, Haneul, Park, Gun-Hoo, Shao, Zhicheng, Guan, Youxin, Park, James M., Yu, Sophy, Park, Joy S., Coyle, Joseph T., Weinberger, Daniel R., Straub, Richard E., Cohen, Bruce M., McPhie, Donna L., Yin, Changhong, Huang, Weihua, Kim, Hae-Young, Chung, Sangmi
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813882/
https://ncbi.nlm.nih.gov/pubmed/31019265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-019-0423-3
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