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Role of Mouse Cytochrome P450 Enzymes of the Cyp2abfgs Subfamilies in the Induction of Lung Inflammation by Cigarette Smoke Exposure

Many constituents of tobacco smoke (TS) require bioactivation to exert toxic effects; however, few studies have examined the role of bioactivation enzymes in the adverse effects of TS exposure. This knowledge gap is a major source of uncertainty for risk assessment and chemoprevention efforts. Our a...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Hartog, Matthew, Zhang, Qing-Yu, Ding, Xinxin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813748/
https://ncbi.nlm.nih.gov/pubmed/31388674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz171
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