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Differential Expression of Cytochrome P450 Enzymes from the CYP2C Subfamily in the Human Brain

Cytochrome P450 enzymes from the CYP2C subfamily play a prominent role in the metabolic clearance of many drugs. CYP2C enzymes have also been implicated in the metabolism of arachidonic acid to vasoactive epoxyeicosatrienoic acids. CYP2C8, CYP2C9, and CYP2C19 are expressed in the adult liver at sign...

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Dades bibliogràfiques
Publicat a:Drug Metab Dispos
Autors principals: Booth Depaz, Iris M., Toselli, Francesca, Wilce, Peter A., Gillam, Elizabeth M. J.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067382/
https://ncbi.nlm.nih.gov/pubmed/25504503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.114.061242
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