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Differential Expression of Cytochrome P450 Enzymes from the CYP2C Subfamily in the Human Brain

Cytochrome P450 enzymes from the CYP2C subfamily play a prominent role in the metabolic clearance of many drugs. CYP2C enzymes have also been implicated in the metabolism of arachidonic acid to vasoactive epoxyeicosatrienoic acids. CYP2C8, CYP2C9, and CYP2C19 are expressed in the adult liver at sign...

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Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Main Authors: Booth Depaz, Iris M., Toselli, Francesca, Wilce, Peter A., Gillam, Elizabeth M. J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067382/
https://ncbi.nlm.nih.gov/pubmed/25504503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.114.061242
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