Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus

It is assumed that intracellular pathogenic bacteria have to cope with DNA alkylating stress within host cells. Here we use single-cell reporter systems to show that the pathogen Brucella abortus does encounter alkylating stress during the first hours of macrophage infection. Genes encoding direct r...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Poncin, Katy, Roba, Agnès, Jimmidi, Ravikumar, Potemberg, Georges, Fioravanti, Antonella, Francis, Nayla, Willemart, Kévin, Zeippen, Nicolas, Machelart, Arnaud, Biondi, Emanuele G., Muraille, Eric, Vincent, Stéphane P., De Bolle, Xavier
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813329/
https://ncbi.nlm.nih.gov/pubmed/31649248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12516-8
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