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Chronic Brucella Infection Induces Selective and Persistent Interferon Gamma-Dependent Alterations of Marginal Zone Macrophages in the Spleen

The spleen is known as an important filter for blood-borne pathogens that are trapped by specialized macrophages in the marginal zone (MZ): the CD209(+) MZ macrophages (MZMs) and the CD169(+) marginal metallophilic macrophages (MMMs). Acute systemic infection strongly impacts MZ populations and the...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Machelart, Arnaud, Khadrawi, Abir, Demars, Aurore, Willemart, Kevin, De Trez, Carl, Letesson, Jean-Jacques, Muraille, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649024/
https://ncbi.nlm.nih.gov/pubmed/28808159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00115-17
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