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Lysosome restoration to activate podocyte autophagy: a new therapeutic strategy for diabetic kidney disease
Autophagy, the intracellular lysosomal degradation process plays a pivotal role in podocyte homeostasis in diabetic kidney disease (DKD). Lysosomal function, autophagic activity, and their actions were investigated in vitro and in vivo. We found that LC3-II- and p62-positive vacuoles accumulated in...
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| Udgivet i: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6813305/ https://ncbi.nlm.nih.gov/pubmed/31649253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2002-6 |
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