Molecular profiling of rheumatoid arthritis patients reveals an association between innate and adaptive cell populations and response to anti-tumor necrosis factor

BACKGROUND: The goal of this study is to use comprehensive molecular profiling to characterize clinical response to anti-TNF therapy in a real-world setting and identify reproducible markers differentiating good responders and non-responders in rheumatoid arthritis (RA). METHODS: Whole-blood mRNA, p...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Farutin, Victor, Prod’homme, Thomas, McConnell, Kevin, Washburn, Nathaniel, Halvey, Patrick, Etzel, Carol J., Guess, Jamey, Duffner, Jay, Getchell, Kristen, Meccariello, Robin, Gutierrez, Bryan, Honan, Christopher, Zhao, Ganlin, Cilfone, Nicholas A., Gunay, Nur Sibel, Hillson, Jan L., DeLuca, David S., Saunders, Katherine C., Pappas, Dimitrios A., Greenberg, Jeffrey D., Kremer, Joel M., Manning, Anthony M., Ling, Leona E., Capila, Ishan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813112/
https://ncbi.nlm.nih.gov/pubmed/31647025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-019-1999-3
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