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Thymically-derived Foxp3(+) regulatory T cells are the primary regulators of type 1 diabetes in the non-obese diabetic mouse model

Regulatory T cells (Tregs) are an immunosuppressive population that are identified based on the stable expression of the fate-determining transcription factor forkhead box P3 (Foxp3). Tregs can be divided into distinct subsets based on whether they developed in the thymus (tTregs) or in the peripher...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Holohan, Daniel R., Van Gool, Frédéric, Bluestone, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812862/
https://ncbi.nlm.nih.gov/pubmed/31647813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217728
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