A drug interaction study investigating the effect of Rifabutin on the pharmacokinetics of Maraviroc in healthy subjects

Effects of steady-state rifabutin on the pharmacokinetics of steady-state maraviroc were investigated in fourteen healthy adult female and male volunteers. Maraviroc 300 mg twice daily (BID) was given orally with food for fifteen days. On day six, rifabutin 300 mg once daily (QD, P.O.) was added to...

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Udgivet i:PLoS One
Main Authors: Ghannad, M., Dennehy, M., la Porte, C., Seguin, I., Tardiff, D., Mallick, R., Sabri, E., Zhang, G., Kanji, S., Cameron, D. W.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812819/
https://ncbi.nlm.nih.gov/pubmed/31647836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223969
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