A drug interaction study investigating the effect of Rifabutin on the pharmacokinetics of Maraviroc in healthy subjects

Effects of steady-state rifabutin on the pharmacokinetics of steady-state maraviroc were investigated in fourteen healthy adult female and male volunteers. Maraviroc 300 mg twice daily (BID) was given orally with food for fifteen days. On day six, rifabutin 300 mg once daily (QD, P.O.) was added to...

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Veröffentlicht in:PLoS One
Hauptverfasser: Ghannad, M., Dennehy, M., la Porte, C., Seguin, I., Tardiff, D., Mallick, R., Sabri, E., Zhang, G., Kanji, S., Cameron, D. W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812819/
https://ncbi.nlm.nih.gov/pubmed/31647836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223969
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