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Sirtuins and FoxOs in Osteoporosis and Osteoarthritis

The sirtuin family of NAD(+)-dependent protein deacetylases promotes longevity and counteract age-related diseases. One of the major targets of Sirtuins are the FoxO family of transcription factors. FoxOs play a major role in the adaptation of cells to a variety of stressors such as oxidative stress...

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Bibliografiske detaljer
Udgivet i:Bone
Main Authors: Almeida, Maria, Porter, Ryan M.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812652/
https://ncbi.nlm.nih.gov/pubmed/30738214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.01.018
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