The coronary artery disease risk-associated Plpp3 gene and its product lipid phosphate phosphatase 3 regulate experimental atherosclerosis

OBJECTIVE: Genome wide association studies identified novel loci in phospholipid phosphatase 3 (PLPP3) that associate with coronary artery disease (CAD) risk independently of traditional risk factors. PLPP3 encodes lipid phosphate phosphatase 3 (LPP3), a cell surface enzyme that can regulate the ava...

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Pubblicato in:Arterioscler Thromb Vasc Biol
Autori principali: Mueller, Paul A., Yang, Liping, Ubele, Margo, Mao, Guogen, Brandon, Jason, Vandra, Julia, Nichols, Timothy C., Escalante-Alcalde, Diana, Morris, Andrew J., Smyth, Susan S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812632/
https://ncbi.nlm.nih.gov/pubmed/31533471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.313056
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