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Simvastatin improves lysosome function via enhancing lysosome biogenesis in endothelial cells

Nlrp3 inflammasomes were shown to play a critical role in triggering obesity-associated early onsets of cardiovascular complications such as endothelial barrier dysfunction with endothelial hyperpermeability. Statins prevent endothelial dysfunction and decrease cardiovascular risk in patients with o...

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Bibliographic Details
Published in:Front Biosci (Landmark Ed)
Main Authors: Zhang, Youzhi, Wang, Yun-Ting, Koka, Saisudha, Zhang, Yang, Hussain, Tahir, Li, Xiang
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812495/
https://ncbi.nlm.nih.gov/pubmed/31585890
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