Local controlled release of corticosteroids extends surgically induced joint instability by inhibiting tissue healing

BACKGROUND AND PURPOSE: Corticosteroids are intra‐articularly injected to relieve pain in joints with osteoarthritis (OA) or acute tissue damage such as ligament or tendon tears, despite its unverified contraindication in unstable joints. Biomaterial‐based sustained delivery may prolong reduction of...

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Dades bibliogràfiques
Publicat a:Br J Pharmacol
Autors principals: Rudnik‐Jansen, Imke, Tellegen, Anna R., Pouran, Behdad, Schrijver, Karin, Meij, Björn P., Emans, Pieter J., de Gendt, Erin, Thomas, Rachel E., Kik, Marja J.L., de Visser, Huub M., Weinans, Harrie, Egas, Annelies, van Maarseveen, Erik, Woike, Nina, Mihov, George, Thies, Jens, Tryfonidou, Marianna A., Creemers, Laura B.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811746/
https://ncbi.nlm.nih.gov/pubmed/31378925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14817
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