Intra-articular injection of triamcinolone acetonide releasing biomaterial microspheres inhibits pain and inflammation in an acute arthritis model

Inflammation of the synovium and joint capsule is a main driver of pain in an osteoarthritic (OA) joint. Triamcinolone acetonide (TAA) is a classical corticosteroid that reduces synovitis and alleviates pain, albeit transiently. Biomaterial-based local TAA release may prolong the suppression of pain...

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Vydáno v:Drug Deliv
Hlavní autoři: Rudnik-Jansen, Imke, Schrijver, Karin, Woike, Nina, Tellegen, Anna, Versteeg, Sabine, Emans, Pieter, Mihov, George, Thies, Jens, Eijkelkamp, Niels, Tryfonidou, Marianna, Creemers, Laura
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407600/
https://ncbi.nlm.nih.gov/pubmed/30843733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2019.1568625
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