Predicting Functional Responses of Progenitor Cell Exosome Potential with Computational Modeling

Congenital heart disease can lead to severe right ventricular heart failure (RVHF). We have shown that aggregated c‐kit(+) progenitor cells (CPCs) can improve RVHF repair, likely due to exosome‐mediated effects. Here, we demonstrate that miRNA content from monolayer (2D) and aggregated (3D) CPC exos...

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Veröffentlicht in:Stem Cells Transl Med
Hauptverfasser: Trac, David, Hoffman, Jessica R., Bheri, Sruti, Maxwell, Joshua T., Platt, Manu O., Davis, Michael E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2019
Schlagworte:
Tissue Engineering and Regenerative Medicine
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811701/
https://ncbi.nlm.nih.gov/pubmed/31385648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.19-0059
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