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Experimental, Systems and Computational Approaches to Understanding the MicroRNA-Mediated Reparative Potential of Cardiac Progenitor Cell-Derived Exosomes From Pediatric Patients

RATIONALE: Studies have demonstrated that exosomes can repair cardiac tissue post myocardial infarction (MI) and recapitulate the benefits of cellular therapy. OBJECTIVE: We evaluated the role of donor age and hypoxia of human pediatric cardiac progenitor cell (CPC)-derived exosomes, in a rat model...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Agarwal, Udit, George, Alex, Bhutani, Srishti, Ghosh-Choudary, Shohini, Maxwell, Joshua, Brown, Milton E., Mehta, Yash, Platt, Manu O., Liang, Yaxuan, Sahoo, Susmita, Davis, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315680/
https://ncbi.nlm.nih.gov/pubmed/27872050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.309935
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