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SPRY4 is responsible for pathogenesis of adolescent idiopathic scoliosis by contributing to osteogenic differentiation and melatonin response of bone marrow-derived mesenchymal stem cells

Adolescent idiopathic scoliosis (AIS) is a complex, three-dimensional deformity of the spine that commonly occurs in pubescent girls. Decreased osteogenic differentiation and aberrant melatonin signalling have been demonstrated in mesenchymal stem cells (MSCs) from AIS patients and are implicated in...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cell Death Dis
Main Authors: Li, Jing, Li, Na, Chen, Yunfei, Hui, Shangyi, Fan, Junfen, Ye, Buqing, Fan, Zusen, Zhang, Jianguo, Zhao, Robert Chunhua, Zhuang, Qianyu
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811559/
https://ncbi.nlm.nih.gov/pubmed/31645544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1949-7
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