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SPRY4 is responsible for pathogenesis of adolescent idiopathic scoliosis by contributing to osteogenic differentiation and melatonin response of bone marrow-derived mesenchymal stem cells

Adolescent idiopathic scoliosis (AIS) is a complex, three-dimensional deformity of the spine that commonly occurs in pubescent girls. Decreased osteogenic differentiation and aberrant melatonin signalling have been demonstrated in mesenchymal stem cells (MSCs) from AIS patients and are implicated in...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell Death Dis
मुख्य लेखकों: Li, Jing, Li, Na, Chen, Yunfei, Hui, Shangyi, Fan, Junfen, Ye, Buqing, Fan, Zusen, Zhang, Jianguo, Zhao, Robert Chunhua, Zhuang, Qianyu
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811559/
https://ncbi.nlm.nih.gov/pubmed/31645544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1949-7
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