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A secreted microRNA disrupts autophagy in distinct tissues of Caenorhabditis elegans upon ageing
Macroautophagy, a key player in protein quality control, is proposed to be systematically impaired in distinct tissues and causes coordinated disruption of protein homeostasis and ageing throughout the body. Although tissue-specific changes in autophagy and ageing have been extensively explored, the...
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| 發表在: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6811558/ https://ncbi.nlm.nih.gov/pubmed/31645592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12821-2 |
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