20S Proteasome as a Drug Target in Trichomonas vaginalis

Trichomoniasis is a sexually transmitted disease with hundreds of millions of annual cases worldwide. Approved treatment options are limited to two related nitro-heterocyclic compounds, yet resistance to these drugs is an increasing concern. New antimicrobials against the causative agent, Trichomona...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: O’Donoghue, Anthony J., Bibo-Verdugo, Betsaida, Miyamoto, Yukiko, Wang, Steven C, Yang, Justin Z., Zuill, Douglas E., Matsuka, Shoun, Jiang, Zhenze, Almaliti, Jehad, Caffrey, Conor R., Gerwick, William H., Eckmann, Lars
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811414/
https://ncbi.nlm.nih.gov/pubmed/31451503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00448-19
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