635. Genomic Evolution and Progression of Antimicrobial Resistance in a Series of Extensively Drug-Resistant Pseudomonas aeruginosa (XDR-Pa) Isolates from a Cystic Fibrosis Lung Transplant Recipient

BACKGROUND: Chronic respiratory infection due to extensively drug-resistant Pseudomonas aeruginosa (XDR-Pa) is a significant cause of mortality in cystic fibrosis (CF) patients. The CF respiratory anatomy, chronic antibiotic use, and PA colonization creates a milieu for high evolutionary pressure an...

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Veröffentlicht in:Open Forum Infect Dis
Hauptverfasser: Yasmin, Mohamad, Adams, Mark D, Marshall, Steven, Abbo, Lilian, Benjamino, Jacquelynn, Krishnan, Nikhil, Rojas, Laura J, Scott, Jacob, Jacobs, Michael, Rhoads, Daniel D, Perez-Cardona, Armando, Martinez, Octavio, Perez, Federico, Bonomo, Robert A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811252/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.703
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