610. Meropenem-vaborbactam (MV) In Vitro Activity Against Carbapenem-Resistant Klebsiella pneumoniae (CRKP) Isolates with Outer Membrane Porin Gene Mutations

BACKGROUND: Vaborbactam is a cyclic boronic acid β-lactamase inhibitor (BLI) developed to potently inhibit Ambler class A&C enzymes, including KPC carbapenemases. Metallo-β-lactamases (MBL) and some Class D oxacillinases (OXA) are not inactivated by vaborbactam. Meropenem-vaborbactam (MV) was re...

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Dettagli Bibliografici
Pubblicato in:Open Forum Infect Dis
Autori principali: Yasmin, Mohamad, Marshall, Steven, Jacobs, Michael, Rhoads, Daniel D, Rojas, Laura J, Perez, Federico, Bonomo, Robert A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6810654/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.679
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