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705. Pharmacokinetics (PK) and Safety of Lefamulin (LEF) After Single Intravenous Dose Administration in Subjects With Impaired Renal Function and in Those Requiring Hemodialysis

BACKGROUND: Renal comorbidities are common in patients hospitalized with community-acquired bacterial pneumonia (CABP). LEF, a novel pleuromutilin antibiotic (IV/oral), was generally well tolerated and noninferior to moxifloxacin in two phase 3 studies of adults with CABP. We investigated the PK and...

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Bibliografische gegevens
Gepubliceerd in:Open Forum Infect Dis
Hoofdauteurs: Wicha, Wolfgang, Marbury, Thomas C, Dowell, James A, Lykens, Lori, Leister, Cathie, Ermer, James, Gelone, Steven P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6810905/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.773
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