2229. Relative Bioavailability of a Single Oral Dose of SUBA-Itraconazole 65 mg Capsule Compared with Conventional Itraconazole 100 mg Capsule Administered Under Fasted and Fed Conditions in Healthy Adult Volunteers

BACKGROUND: Conventional itraconazole (CI) absorption from capsules even under fed conditions is suboptimal (~55%), let alone when fasted. SUBA-itraconazole (SI) is ~1.8x’s more bioavailable than CI at steady-state in a fed condition. There are, however, no data comparing these formulations under a...

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Bibliografiska uppgifter
I publikationen:Open Forum Infect Dis
Huvudupphovsmän: Mudge, Stuart, Lewis, Phoebe, Burnett, Bruce P
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2019
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Abstracts
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6810727/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.1907
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