2764. Generation of a Balanced, Tetravalent Dengue Vaccine Based on Contemporary Strains Using a Computational, Synthetic Biology-Based Platform

BACKGROUND: The WHO estimates that there may be 50 million cases of dengue virus (DENV) infection worldwide every year. There is no safe vaccine against DENV licensed in the United States. The development of a balanced and effective anti-DENV vaccine is vital to preventing morbidity and mortality. C...

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Publicado en:Open Forum Infect Dis
Main Authors: Wang, Ying, Stauft, Charles B, Raviprakash, Kanakatte, Coleman, J Robert, Mueller, Steffen
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6810340/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.2441
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